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Monkeypox (State of Ohio)

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During 2022, cases of monkeypox have been reported in the United States and other countries where monkeypox is not typically found. The first monkeypox case in Ohio was reported in June 2022. Since that time, multiple cases have been identified across the state, with most cases reported in large metropolitan areas. The Ohio Department of Health (ODH) continues to collaborate with public health and healthcare partners to identify cases, ensure appropriate care for patients, and prevent spread of the virus.

People with monkeypox in the current outbreak generally report having close, sustained physical contact with other people who have monkeypox.

For general information about monkeypox, please visit ODH’s Frequently Asked Questions about Monkeypox. Clinicians and local health jurisdictions should refer to the ODH Infectious Disease Control Manual and Centers for Disease Control and Prevention’s Monkeypox website for more detailed information, including diagnostic testing, reporting, treatment, and public health management.


Confirmed monkeypox/orthopoxvirus cases include individuals with detection of monkeypox virus or orthopoxvirus DNA, or detection by genomic sequencing, in clinical specimens.

For specific information on case definition and case classifications status, see the ODH Infectious Disease Control Manual.